CIB1 Antikörper

Produktnummer ABIN965898

Produktdetails anti-CIB1 Antikörper

Target: CIB1 (Calcium and Integrin-Binding Protein 1 (CIB1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CIB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of CIB1 expressed in E. Coli.

Klon: 5A1F5E12-5A1H7E12

Anwendungsinformationen

Applikationshinweise: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-CIB1 Antikörper (ABIN965898)

White, Yang, Monteiro, Foskett: "CIB1, a ubiquitously expressed Ca2+-binding protein ligand of the InsP3 receptor Ca2+ release channel." in: The Journal of biological chemistry, Vol. 281, Issue 30, pp. 20825-33, (2006) (PubMed).

Details zu CIB1

Target: CIB1 (Calcium and Integrin-Binding Protein 1 (CIB1))

Andere Bezeichnung: CIB1 (CIB1 Produkte)

Synonyme: zgc:112015 antikoerper, CIB antikoerper, CIBP antikoerper, KIP1 antikoerper, PRKDCIP antikoerper, SIP2-28 antikoerper, Cibkip antikoerper, Kip antikoerper, Prkdcip antikoerper, Cib antikoerper, Sip2-28 antikoerper, calcium and integrin binding 1 (calmyrin) antikoerper, calcium and integrin-binding protein 1 antikoerper, calcium and integrin binding 1 antikoerper, Calcium and integrin-binding protein 1 antikoerper, cib1 antikoerper, CpipJ_CPIJ003501 antikoerper, CIB1 antikoerper, kip1 antikoerper, Cib1 antikoerper

Hintergrund: CIB1(also designated calcium and integrin binding 1 or calmyrin),with 191-amino acid protein(about 21kDa), belongs to the calcium-binding protein family.CIB1 is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining.CIB1 is an EF-hand-containing protein that binds multiple effector proteins, including the platelet alpha(IIb)beta(3) integrin and several serine/threonine kinases and potentially modulates their function.CIB1 regulates platelet aggregation in hemostasis through a specific interaction with the alpha(IIb) cytoplasmic domain of platelet integrin alpha(IIb)beta(3). CIB1 is also ubiquitously expressed activating and inhibiting protein ligand of the InsP3R.
Synonyms: CIB, KIP, KIP1, SIP228

Gen-ID: 10519