MSH5 Antikörper (AA 508-519)

Produktnummer ABIN962670

Produktdetails anti-MSH5 Antikörper

Target: MSH5 (MutS Homolog 5 (MSH5))

Bindungsspezifität: AA 508-519

Reaktivität: Human, Maus, Huhn, Affe, Xenopus laevis

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser MSH5 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marke: IHC-plus™

Spezifität: Human MSH5. This antibody is expected to recognise three reported isoforms ( NP_079535.3 , NP_751897.1, NP_002432.1), Reported variants NP_751898.1 and NP_002432.1 represent identical protein.

Homologie: Percent identity by BLAST analysis: Human, Gibbon, Monkey, Mouse, Chicken, Xenopus (100%) Rat, Panda, Bovine, Dog, Horse, Pig (92%) Marmoset (83%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide GDLHCEIRDQET from an internal region of human MSH5 (NP_079535.3 , NP_751897.1, NP_002432.1). Percent identity by BLAST analysis: Human, Gibbon, Monkey, Mouse, Chicken, Xenopus (100%), Rat, Panda, Bovine, Dog, Horse, Pig (92%), Marmoset (83%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (2.5 - 3.75 μg/mL), Peptide-ELISA (1:64000)

Usage: Peptide ELISA: antibody detection limit dilution 1:64000. Western Blot: Preliminary experiments gave an approx 38kD band in Human Heart, Tonsil and Thymus lysates after 0.1 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 92.9kD according to the smallest reported isoform NP_002432.1. The 38kD band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies / lysates? Have any further splice variants / modified forms been reported?

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu MSH5

Target: MSH5 (MutS Homolog 5 (MSH5))

Andere Bezeichnung: MSH5 (MSH5 Produkte)

Synonyme: MSH5 antikoerper, G7 antikoerper, MUTSH5 antikoerper, NG23 antikoerper, Mut5 antikoerper, mutS homolog 5 antikoerper, mutS protein homolog 5 antikoerper, MSH (MutS Homolog) family antikoerper, MSH5 antikoerper, msh5 antikoerper, LOC100635155 antikoerper, Msh5 antikoerper, msh-5 antikoerper

Hintergrund: Name/Gene ID: MSH5

Synonyms: MSH5, MutS homolog 5 (E. coli), HMSH5, MutS protein homolog 5, NG23, G7, MutS (E. coli) homolog 5, MUTSH5

Gen-ID: 4439

NCBI Accession: NP_079535, NP_751897, NP_002432

Pathways: M Phase