PAI1 Antikörper (Middle Region)

Produktnummer ABIN954748

Produktdetails anti-PAI1 Antikörper

Target: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Bindungsspezifität: AA 187-216, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: Recognizes SERPINE1 (Center).

Aufreinigung: Protein A column followed by peptide Affinity purification

Immunogen: KLH conjugated synthetic peptide between 187-216 amino acids from the Central region of Human SERPINE1 Genename: SERPINE1

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PAI1

Target: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Andere Bezeichnung: SERPINE1 / PAI1 (SERPINE1 Produkte)

Synonyme: PAI antikoerper, PAI-1 antikoerper, PAI1 antikoerper, PLANH1 antikoerper, SERPINE1 antikoerper, si:ch211-138a11.1 antikoerper, Planh1 antikoerper, PAI1A antikoerper, Pai1 antikoerper, Pai1aa antikoerper, Planh antikoerper, RATPAI1A antikoerper, serpin family E member 1 antikoerper, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 L homeolog antikoerper, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 antikoerper, serine (or cysteine) peptidase inhibitor, clade E, member 1 antikoerper, SERPINE1 antikoerper, serpine1.L antikoerper, serpine1 antikoerper, Serpine1 antikoerper

Hintergrund: This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.Synonyms: Endothelial plasminogen activator inhibitor, PAI, PAI-1, PLANH1, Plasminogen Activator Inhibitor 1, Serpin E1

Gen-ID: 5054

NCBI Accession: NP_000593

Pathways: p53 Signalweg, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagie, Smooth Muscle Cell Migration