PSMB10 Antikörper (C-Term)

Produktnummer ABIN954355

Produktdetails anti-PSMB10 Antikörper

Target: PSMB10 (Proteasome (Prosome, Macropain) Subunit, beta Type 10 (PSMB10))

Bindungsspezifität: AA 213-242, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMB10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human PSMB10 (C-term).

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 213-242 amino acids from the C-terminal region of Human PSMB10

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PSMB10

Target: PSMB10 (Proteasome (Prosome, Macropain) Subunit, beta Type 10 (PSMB10))

Andere Bezeichnung: PSMB10 (PSMB10 Produkte)

Synonyme: Mecl-1 antikoerper, Mecl1 antikoerper, LMP10 antikoerper, MECL1 antikoerper, beta2i antikoerper, proteasome (prosome, macropain) subunit, beta type 10 antikoerper, proteasome subunit beta 10 antikoerper, Psmb10 antikoerper, PSMB10 antikoerper

Hintergrund: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome.Synonyms: EC=3.4.25.1, MECL1, Macropain subunit MECl-1, Multicatalytic endopeptidase complex subunit MECl-1, PSMB10, Proteasome MECl-1, Proteasome subunit beta type-10, Proteasome subunit beta-2i

Molekulargewicht: 28936 Da

Gen-ID: 5699

NCBI Accession: NP_002792

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA