PSMB10 Antikörper (C-Term)

Produktnummer ABIN656500

Produktdetails anti-PSMB10 Antikörper

Target: PSMB10 (Proteasome (Prosome, Macropain) Subunit, beta Type 10 (PSMB10))

Bindungsspezifität: AA 214-242, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMB10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PSMB10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-242 amino acids from the C-terminal region of human PSMB10.

Klon: RB31189

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: PSMB10 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu PSMB10

Target: PSMB10 (Proteasome (Prosome, Macropain) Subunit, beta Type 10 (PSMB10))

Andere Bezeichnung: PSMB10 (PSMB10 Produkte)

Synonyme: Mecl-1 antikoerper, Mecl1 antikoerper, LMP10 antikoerper, MECL1 antikoerper, beta2i antikoerper, proteasome (prosome, macropain) subunit, beta type 10 antikoerper, proteasome subunit beta 10 antikoerper, Psmb10 antikoerper, PSMB10 antikoerper

Hintergrund: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome.

Molekulargewicht: 28936

Gen-ID: 5699

NCBI Accession: NP_002792

UniProt: P40306

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA