PIGA Antikörper (C-Term)

Produktnummer ABIN954134

Produktdetails anti-PIGA Antikörper

Target: PIGA (Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA))

Bindungsspezifität: AA 147-177, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIGA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes PIGA at C-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Purified through a Protein A column followed by peptide affinity purification

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 147-177aa) of human PIGA.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PIGA

Target: PIGA (Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA))

Andere Bezeichnung: PIGA (PIGA Produkte)

Synonyme: GPI3 antikoerper, MCAHS2 antikoerper, PIG-A antikoerper, AI194334 antikoerper, Pig-a antikoerper, im:6911675 antikoerper, zgc:56589 antikoerper, phosphatidylinositol glycan anchor biosynthesis class A antikoerper, phosphatidylinositol glycan anchor biosynthesis, class A antikoerper, PIGA antikoerper, Piga antikoerper, piga antikoerper

Hintergrund: The PIGA gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized. A related pseudogene is located on chromosome 12.Synonyms: GlcNAc-PI synthesis protein, PIG-A, Phosphatidylinositol N-acetylglucosaminyltransferase subunit A, Phosphatidylinositol-glycan biosynthesis class A protein

Gen-ID: 5277

NCBI Accession: NP_002632

Pathways: Inositol Metabolic Process