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NCOA1 Antikörper (Middle Region)
NCOA1
Reaktivität: Human
WB, EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-NCOA1 Antikörper
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Target
Alle NCOA1 Antikörper anzeigen
NCOA1
(Nuclear Receptor Coactivator 1 (NCOA1))
Bindungsspezifität
Alle Epitope für NCOA1 Antikörper
AA 593-625, Middle Region
Reaktivität
Alle Reaktivitäten für NCOA1 Antikörper
Human
Wirt
Alle Wirte für NCOA1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für NCOA1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für NCOA1 Antikörper
Dieser NCOA1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für NCOA1 Antikörper
Western Blotting (WB), Enzyme Immunoassay (EIA)
Spezifität
This antibody recognizes NCOA1/SRC1.
Kreuzreaktivität (Details)
Species reactivity (tested):Human
Aufreinigung
Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Immunogen
Synthetic peptide - KLH conjugated - corresponding to the central region (between 593-625aa) of human NCOA1 / SRC1.
Isotyp
Ig Fraction
Top Product
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Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu NCOA1
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Target
NCOA1
(Nuclear Receptor Coactivator 1 (NCOA1))
Andere Bezeichnung
NCOA1 (NCOA1 Produkte )
Synonyme
F-SRC-1 antikoerper, KAT13A antikoerper, RIP160 antikoerper, SRC1 antikoerper, bHLHe42 antikoerper, bHLHe74 antikoerper, si:dkey-5g7.6 antikoerper, si:dkey-34f16.6 antikoerper, NCOA1 antikoerper, SRC-1 antikoerper, nuclear receptor coactivator 1 antikoerper, NCOA1 antikoerper, ncoa1 antikoerper, Ncoa1 antikoerper
Hintergrund
The protein encoded by the NCOA1 gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified.Synonyms: BHLHE74, Class E basic helix-loop-helix protein 74, NCoA-1, NY-REN-52, Nuclear receptor coactivator 1, Protein Hin-2, RIP160, SRC-1, Steroid receptor coactivator 1
Gen-ID
8648
NCBI Accession
NP_003734
Pathways
Intracellular Steroid Hormone Receptor Signaling Pathway , Nuclear Hormone Receptor Binding , Chromatin Binding , Regulation of Lipid Metabolism by PPARalpha
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