NCOA1 Antikörper (C-Term)

Produktnummer ABIN391825

Produktdetails anti-NCOA1 Antikörper

Target: NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))

Bindungsspezifität: AA 1338-1367, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCOA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Pig

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This SRC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1338-1367 amino acids from the C-terminal region of human SRC1.

Klon: RB14368

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu NCOA1

Target: NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))

Andere Bezeichnung: SRC1 (NCOA1 Produkte)

Synonyme: F-SRC-1 antikoerper, KAT13A antikoerper, RIP160 antikoerper, SRC1 antikoerper, bHLHe42 antikoerper, bHLHe74 antikoerper, si:dkey-5g7.6 antikoerper, si:dkey-34f16.6 antikoerper, NCOA1 antikoerper, SRC-1 antikoerper, nuclear receptor coactivator 1 antikoerper, NCOA1 antikoerper, ncoa1 antikoerper, Ncoa1 antikoerper

Hintergrund: SRC1 acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. This protein binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion.

Molekulargewicht: 156757

Gen-ID: 8648

NCBI Accession: NP_003734, NP_671756, NP_671766

UniProt: Q15788

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha