NCOA1 Antikörper

Produktnummer ABIN932473

Dieser Maus Monoklonal Antikörper detektiert spezifisch NCOA1 in DB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für NCOA1 Antikörper (ABIN932473)

Target: NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NCOA1 Antikörper ist unkonjugiert

Applikation: Dot Blot (DB)

Klon: 3532C6a

Produktdetails anti-NCOA1 Antikörper

Kreuzreaktivität: Human

Kreuzreaktivität (Details): Other species not studied.

Aufreinigung: Protein G affinity chromatography

Immunogen: NCOA1 antibody was raised in mouse using recombinant Human Nuclear Receptor Coactivator 1 (Ncoa1)

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: NCOA1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Details zu NCOA1

Target: NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))

Andere Bezeichnung: NCOA1

Hintergrund: The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. Synonyms: Monoclonal NCOA1 antibody, Anti-NCOA1 antibody, Nuclear receptor coactivator 1 antibody, SRC1 antibody, SRC-1 antibody, KAT13A antibody, NCoA-1 antibody, RIP160 antibody, F-SRC-1 antibody, MGC129719 antibody, MGC129720 antibody.

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha