IRF4 Antikörper (Middle Region)

Produktnummer ABIN952951

Produktdetails anti-IRF4 Antikörper

Target: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Bindungsspezifität: AA 171-199, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human IRF4 (Center).

Aufreinigung: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: KLH conjugated synthetic peptide between 171-199 amino acids from the Central region of human IRF4

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu IRF4

Target: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Andere Bezeichnung: IRF4 (IRF4 Produkte)

Synonyme: LSIRF antikoerper, MUM1 antikoerper, NF-EM5 antikoerper, AI385587 antikoerper, IRF-4 antikoerper, Spip antikoerper, IRF4 antikoerper, si:ch73-170d1.2 antikoerper, irf4 antikoerper, interferon regulatory factor 4 antikoerper, interferon regulatory factor 4a antikoerper, Interferon regulatory factor 4 antikoerper, PWWP domain-containing protein MUM1 antikoerper, IRF4 antikoerper, Irf4 antikoerper, irf4a antikoerper, irf4 antikoerper, LOC612320 antikoerper, LOC100068881 antikoerper

Hintergrund: The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6,14)(p25,q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.Synonyms: Interferon regulatory factor 4, LSIRF, Lymphocyte-specific interferon regulatory factor, MUM1, Multiple myeloma oncogene 1, NF-EM5

Molekulargewicht: 51772 Da

Gen-ID: 3662

NCBI Accession: NP_001182215

Pathways: Chromatin Binding