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GAD65 Antikörper (Middle Region)
GAD2
Reaktivität: Human
WB, IF, IHC (p), EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-GAD65 Antikörper
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Target
Alle GAD65 (GAD2) Antikörper anzeigen
GAD65 (GAD2)
(Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
Bindungsspezifität
Alle Epitope für GAD65 Antikörper
AA 116-145, Middle Region
Reaktivität
Alle Reaktivitäten für GAD65 Antikörper
Human
Wirt
Alle Wirte für GAD65 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für GAD65 Antikörper
Polyklonal
Konjugat
Alle Konjugate für GAD65 Antikörper
Dieser GAD65 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für GAD65 Antikörper
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Spezifität
This antibody recognizes Human GAD2 / GAD65 (Center).
Aufreinigung
Protein A column, followed by peptide affinity purification
Immunogen
KLH conjugated synthetic peptide between 116-145 amino acids from the Central region of Human GAD2 / GAD65 Genename: GAD2
Isotyp
Ig Fraction
Top Product
Discover our top product GAD2 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu GAD65
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Target
GAD65 (GAD2)
(Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
Andere Bezeichnung
GAD2 / GAD65 (GAD2 Produkte )
Synonyme
GAD65 antikoerper, gad65 antikoerper, F12P19.12 antikoerper, F12P19_12 antikoerper, GLUTAMATE DECARBOXYLASE 2 antikoerper, glutamate decarboxylase 2 antikoerper, zgc:112198 antikoerper, 6330404F12Rik antikoerper, GAD(65) antikoerper, Gad-2 antikoerper, glutamate decarboxylase 2 antikoerper, glutamate decarboxylase 1 antikoerper, glutamic acid decarboxylase 2 antikoerper, GAD2 antikoerper, PTRG_06148 antikoerper, LOC9324534 antikoerper, Gad2 antikoerper, GAD1 antikoerper, gad2 antikoerper
Hintergrund
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.Synonyms: 65 kDa glutamic acid decarboxylase, GAD-2, GAD-65, Glutamate decarboxylase 2, Glutamate decarboxylase 65 kDa isoform
Molekulargewicht
65411 Da
Gen-ID
2572
NCBI Accession
NP_000809
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