GBA3 Antikörper (C-Term)

Produktnummer ABIN951831

Produktdetails anti-GBA3 Antikörper

Target: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Bindungsspezifität: AA 295-325, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GBA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human Cytosolic beta-glucosidase (C-term).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 295-325 amino acids from the C-terminal region of Human Cytosolic beta-glucosidase Genename: GBA3

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu GBA3

Target: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Andere Bezeichnung: Cytosolic beta-Glucosidase (GBA3 Produkte)

Synonyme: im:6912508 antikoerper, CBG antikoerper, CBGL1 antikoerper, GLUC antikoerper, KLRP antikoerper, glucosylceramidase beta 3 antikoerper, glucosidase, beta, acid 3 (gene/pseudogene) antikoerper, glucosidase, beta, acid 3 (cytosolic) antikoerper, cytosolic beta-glucosidase antikoerper, glucosylceramidase beta 3 (gene/pseudogene) antikoerper, Gba3 antikoerper, gba3 antikoerper, GBA3 antikoerper, LOC100344458 antikoerper

Hintergrund: GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides (de Graaf et al., 2001 [PubMed 11389701]). GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism (Hayashi et al., 2007 [PubMed 17595169]).Synonyms: CBG, CBGL1, Cytosolic beta-glucosidase-like protein 1, GBA3

Molekulargewicht: 53696 Da

Gen-ID: 57733

NCBI Accession: NP_001121904