GBA3 Antikörper (C-Term)

Produktnummer ABIN656223

Produktdetails anti-GBA3 Antikörper

Target: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Bindungsspezifität: AA 296-325, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GBA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GBA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-325 amino acids from the C-terminal region of human GBA3.

Klon: RB31046

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: GBA3 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu GBA3

Target: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Andere Bezeichnung: GBA3 (GBA3 Produkte)

Synonyme: im:6912508 antikoerper, CBG antikoerper, CBGL1 antikoerper, GLUC antikoerper, KLRP antikoerper, glucosylceramidase beta 3 antikoerper, glucosidase, beta, acid 3 (gene/pseudogene) antikoerper, glucosidase, beta, acid 3 (cytosolic) antikoerper, cytosolic beta-glucosidase antikoerper, glucosylceramidase beta 3 (gene/pseudogene) antikoerper, Gba3 antikoerper, gba3 antikoerper, GBA3 antikoerper, LOC100344458 antikoerper

Hintergrund: GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides (de Graaf et al., 2001 [PubMed 11389701]). GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism (Hayashi et al., 2007 [PubMed 17595169]).

Molekulargewicht: 53696

Gen-ID: 57733

NCBI Accession: NP_001121904, NP_001264154, NP_066024

UniProt: Q9H227