GBA3 Antikörper (N-Term)

Produktnummer ABIN2787250

Der Kaninchen Polyklonal anti-GBA3 Antikörper (ABIN2787250) detektiert spezifisch GBA3 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen, Schwein und Kaninchen.

Kurzübersicht für GBA3 Antikörper (N-Term) (ABIN2787250)

Target: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Reaktivität: Human, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GBA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GBA3 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: GBA3 Antibody - N-terminal region

Sequenz: LTHYRFSLSW SRLLPDGTTG FINQKGIDYY NKIIDDLLKN GVTPIVTLYH

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GBA3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GBA3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57505-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu GBA3

Target: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Andere Bezeichnung: GBA3

Hintergrund:

Background Information: GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides (de Graaf et al., 2001 [PubMed 11389701]). GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism (Hayashi et al., 2007 [PubMed 17595169]).

Gene Name: Glucosidase, beta, acid 3 (cytosolic)

Alternative Symbols: CBG, GLUC, KLRP, CBGL1

Protein Name: Cytosolic beta-glucosidase

Molekulargewicht: 54kDa

Gen-ID: 57733

NCBI Accession: NP_066024

UniProt: Q9H227