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CD80 Antikörper

CD80 Reaktivität: Maus FACS Wirt: Ratte Monoclonal RMMP-1 unconjugated
Produktnummer ABIN951413
  • Target Alle CD80 Antikörper anzeigen
    CD80
    Reaktivität
    • 138
    • 108
    • 44
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 87
    • 71
    • 23
    • 18
    • 17
    • 1
    • 1
    Ratte
    Klonalität
    • 138
    • 77
    • 2
    Monoklonal
    Konjugat
    • 86
    • 18
    • 17
    • 15
    • 13
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD80 Antikörper ist unkonjugiert
    Applikation
    • 128
    • 93
    • 69
    • 35
    • 34
    • 22
    • 14
    • 13
    • 13
    • 13
    • 11
    • 11
    • 10
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    This antibody recognises the murine CD80 cell surface protein, also known as B7-1.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Mouse.
    Aufreinigung
    Purified
    Klon
    RMMP-1
    Isotyp
    IgG2a
    Top Product
    Discover our top product CD80 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.1 mg/mL
    Buffer
    PBS containing 0.09 % Sodium Azide as preservative and EIA grade BSA to bring total protein concentration to 4-5 mg/mL
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    DO NOT FREEZE! This product is photosensitive and should be protected from light.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    CD80
    Andere Bezeichnung
    CD80 (CD80 Produkte)
    Synonyme
    B7 antikoerper, B7-1 antikoerper, B7.1 antikoerper, BB1 antikoerper, CD28LG antikoerper, CD28LG1 antikoerper, LAB7 antikoerper, B71 antikoerper, Cd28l antikoerper, Ly-53 antikoerper, Ly53 antikoerper, MIC17 antikoerper, TSA1 antikoerper, CD80 molecule antikoerper, Cd80 molecule antikoerper, CD80 antigen antikoerper, CD80 antikoerper, Cd80 antikoerper
    Hintergrund
    CD80 is a member of the Ig superfamily, along with CD86 (B7-2), participates in T cell costimulation via interactions with CD28 and CTLA-4. CD80 is constitutively expressed on dendritic cells, monocytes, and peritoneal macrophages, and it is inducible on B cells by various means, including activation by LPS, IL-4, and the cross-linking of surface Ig. Expression of CD80 is greatly enhanced on splenic B cells following activation by LPS, with peak expression occurring between 48 and 72 hours. It has been reported that activation of purified B cells with LPS can induce CD80 expression in as few as 18 hours.Synonyms: Activation B7-1 antigen, B7-1, B7.1, BB1, CD28LG, CD28LG1, CTLA-4 counter-receptor B7.1, LAB7, T-lymphocyte activation antigen CD80
    Gen-ID
    12519
    NCBI Accession
    NP_033985
    UniProt
    Q00609
    Pathways
    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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