CACNB2 Antikörper (C-Term)

Produktnummer ABIN950993

Produktdetails anti-CACNB2 Antikörper

Target: CACNB2 (Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2))

Bindungsspezifität: AA 565-579, C-Term

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser CACNB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: ECNKQRSRHK SKDRY

Spezifität: Recognizes CACNB2 (565-579). This antibody is expected to recognize all reported isoforms (NP_000715.2, NP_963890.2, NP_963884.2, NP_963891.1, NP_963887.2, NP_963865.2, NP_963864.1, NP_963866.2, NP_001161417.1).

Kreuzreaktivität (Details): Species reactivity (expected):Rat, Dog, Cow.
Species reactivity (tested):Human, Mouse.

Aufreinigung: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the C Terminus of the protein sequence according to NP_000715.2, NP_963890.2, NP_963884.2, NP_963891.1, NP_963887.2, NP_963865.2, NP_963864.1, NP_963866.2, NP_001161417.1. Genename: CACNB2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris buffered saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CACNB2

Target: CACNB2 (Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2))

Andere Bezeichnung: CACNB2 (CACNB2 Produkte)

Synonyme: CACNLB2 antikoerper, CAVB2 antikoerper, MYSB antikoerper, AW060387 antikoerper, CAB2 antikoerper, Cavbeta2 antikoerper, Cchb2 antikoerper, Cacnlb2 antikoerper, Cacnb2 antikoerper, CACNB2 antikoerper, CACNB2.2 antikoerper, cacnb2a antikoerper, im:7141271 antikoerper, si:dkey-32m20.2 antikoerper, calcium voltage-gated channel auxiliary subunit beta 2 antikoerper, calcium channel, voltage-dependent, beta 2 subunit antikoerper, calcium channel, voltage-dependent, beta 2b antikoerper, CACNB2 antikoerper, Cacnb2 antikoerper, cacnb2b antikoerper

Hintergrund: Heterologous expression studies have shown that the activity of voltage-gated Ca2+ channels is regulated by their beta subunits in a beta subunit isoform-specific manner. Our data show that all four beta subunit isoforms associate with L-type Ca2+ channels in mammalian brain. This beta subunit heterogeneity may play an important role for the fine tuning of L-type channel function and modulation in neurons.Synonyms: CAB2, CACNLB2, Calcium channel voltage-dependent subunit beta 2, Lambert-Eaton myasthenic syndrome antigen B, MYSB, Voltage-dependent L-type calcium channel subunit beta-2

Gen-ID: 783

NCBI Accession: NP_000715

Pathways: Skeletal Muscle Fiber Development