CACNB2 Antikörper (AA 189-205) (HRP)

Produktnummer ABIN2485040

Produktdetails anti-CACNB2 Antikörper (HRP)

Target: CACNB2 (Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2))

Bindungsspezifität: AA 189-205

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CACNB2 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Antibody Array (AA)

Spezifität: Detects ~78 kDa. No cross reactivity against Cavβ1, Cavβ3, Cavβ4.

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Protein G Purified

Immunogen: Synthetic peptide amino acids 189-205 of rat CavBeta2

Klon: N8b-1 (Formerly S8B-1)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

• WB (1:1000)
• IHC (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Kommentare:

1 μg/ml of ABIN2485040 was sufficient for detection of Cavβ2 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Conjugated antibodies should be stored at 4°C

Details zu CACNB2

Target: CACNB2 (Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2))

Andere Bezeichnung: CavBeta2 (CACNB2 Produkte)

Synonyme: CACNLB2 antikoerper, CAVB2 antikoerper, MYSB antikoerper, AW060387 antikoerper, CAB2 antikoerper, Cavbeta2 antikoerper, Cchb2 antikoerper, Cacnlb2 antikoerper, Cacnb2 antikoerper, CACNB2 antikoerper, CACNB2.2 antikoerper, cacnb2a antikoerper, im:7141271 antikoerper, si:dkey-32m20.2 antikoerper, calcium voltage-gated channel auxiliary subunit beta 2 antikoerper, calcium channel, voltage-dependent, beta 2 subunit antikoerper, calcium channel, voltage-dependent, beta 2b antikoerper, CACNB2 antikoerper, Cacnb2 antikoerper, cacnb2b antikoerper

Hintergrund: Cav Beat subunits are involved in the transport of the pore forming alpha1 subunit to the plasma membrane (1). They also shield an ER Retention signal on the alpha1 subunit, thereby guiding the pore-forming subunit to the target membrane (2, 3). They also determine the biophysical properties of the calcium channel (3).

Gen-ID: 116600

NCBI Accession: NP_446303

UniProt: Q8VGC3

Pathways: Skeletal Muscle Fiber Development