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alpha Fetoprotein Antikörper

AFP Reaktivität: Human IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN950378
  • Target Alle alpha Fetoprotein (AFP) Antikörper anzeigen
    alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))
    Reaktivität
    • 233
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    • 15
    • 4
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    Human
    Wirt
    • 141
    • 135
    • 7
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    Kaninchen
    Klonalität
    • 151
    • 134
    • 2
    Polyklonal
    Konjugat
    • 135
    • 37
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser alpha Fetoprotein Antikörper ist unkonjugiert
    Applikation
    • 152
    • 121
    • 87
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    • 15
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    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    Recognizes Alpha-fetoprotein (AFP).
    Cellular Localization: Cytoplasmic.
    Aufreinigung
    Purified
    Immunogen
    Human Alpha-Fetoprotein purified from Human cord serum
    Top Product
    Discover our top product AFP Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))
    Abstract
    AFP Produkte
    Synonyme
    FETA antikoerper, HPAFP antikoerper, alpha fetoprotein antikoerper, alpha-fetoprotein antikoerper, AFP antikoerper, Afp antikoerper
    Hintergrund
    This is a major plasma protein produced by the yolk sac and the liver during fetal life. alpha Fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha Fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha Fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. alpha Fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha Fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasm, especially yolk sac tumors.Synonyms: Alpha-1-fetoprotein, Alpha-fetoglobulin, HPAFP
    Gen-ID
    20371
    NCBI Accession
    NP_001186276
    UniProt
    P02771
    Pathways
    C21-Steroid Hormone Metabolic Process
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