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alpha Fetoprotein Antikörper

AFP Reaktivität: Human WB, ELISA, IHC (p), RIA Wirt: Maus Monoclonal AFP-11 unconjugated
Produktnummer ABIN93887
  • Target Alle alpha Fetoprotein (AFP) Antikörper anzeigen
    alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))
    Reaktivität
    • 242
    • 52
    • 47
    • 28
    • 23
    • 15
    • 4
    • 4
    • 4
    • 2
    • 1
    Human
    Wirt
    • 146
    • 139
    • 7
    • 4
    • 2
    Maus
    Klonalität
    • 153
    • 141
    • 2
    Monoklonal
    Konjugat
    • 143
    • 38
    • 30
    • 17
    • 9
    • 9
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser alpha Fetoprotein Antikörper ist unkonjugiert
    Applikation
    • 156
    • 124
    • 88
    • 71
    • 54
    • 34
    • 30
    • 29
    • 28
    • 27
    • 16
    • 16
    • 15
    • 10
    • 9
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Radioimmunoassay (RIA)
    Spezifität
    The mouse monoclonal antibody AFP-11 reacts with human alpha-Fetoprotein (AFP), a 70 kDa oncofetal antigen. AFP is a major fetal plasma protein, but is not present in healthy adult tissues. Elevated AFP concentrations in adult plasma may be an early marker of hepatocellular carcinoma or teratoblastoma, while high concentrations in amniotic fluid may indicate severe congenital defects of a fetus.
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Reinheit
    > 95 % (by SDS-PAGE)
    Immunogen
    purified alpha-Fetoprotein
    Klon
    AFP-11
    Isotyp
    IgG1
    Top Product
    Discover our top product AFP Primärantikörper
  • Applikationshinweise
    ELISA: The antibody AFP-11 has been tested as the capture antibody in a sandwich ELISA for analysis of human alpha-fetoprotein in combination with antibody AFP-01 (cat. no. 11-259-C100).
    Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/mL, positive tissue: hepatocellular carcinoma, heat mediated antigen retrieval (sodium citrate buffer), mAb incubation 1 hour / RT, detection DAB.
    Western blotting: Recommended dilution: 2 μg/mL, non-reducing conditions.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Target
    alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))
    Andere Bezeichnung
    alpha-Fetoprotein (AFP Produkte)
    Synonyme
    FETA antikoerper, HPAFP antikoerper, alpha fetoprotein antikoerper, alpha-fetoprotein antikoerper, AFP antikoerper, Afp antikoerper
    Hintergrund
    Alpha fetoprotein,Alpha-fetoprotein (AFP) is present in fetal plasma, and it binds e.g. copper, nickel, and bilirubin. Measuring of alpha-fetoprotein level in amniotic fluid can reveal severe fetal defects. In adults, elevated AFP concentrations in the plasma can indicate hepatocellular carcinoma or teratoblastoma. In some individuals, hereditary persistance of alpha-fetoprotein can be observed without any obvious pathology.,AFP, FETA, HPAFP
    Gen-ID
    174
    UniProt
    P02771
    Pathways
    C21-Steroid Hormone Metabolic Process
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