CYP1A1 Antikörper (AA 1-512)

Produktnummer ABIN947763

Produktdetails anti-CYP1A1 Antikörper

Target: CYP1A1 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1))

Bindungsspezifität: AA 1-512

Reaktivität: Human

Wirt: Maus

Klonalität: Polyklonal

Konjugat: Dieser CYP1A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Mouse polyclonal antibody raised against a full-length human CYP1A1 protein.

Sequenz: MLFPISMSAT EFLLASVIFC LVFWVIRASR PQVPKGLKNP PGPWGWPLIG HMLTLGKNPH LALSRMSQQY GDVLQIRIGS TPVVVLSGLD TIRQALVRQG DDFKGRPDLY TFTLISNGQS MSFSPDSGPV WAARRRLAQN GLKSFSIASD PASSTSCYLE EHVSKEAEVL ISTLQELMAG PGHFNPYRYV VVSVTNVICA ICFGRRYDHN HQELLSLVNL NNNFGEVVGS GNPADFIPIL RYLPNPSLNA FKDLNEKFYS FMQKMVKEHY KTFEKGHIRD ITDSLIEHCQ EKQLDENANV QLSDEKIINI VLDLFGAGFD TVTTAISWSL MYLVMNPRVQ RKIQEELDTV IGRSRRPRLS DRSHLPYMEA FILETFRHSS FVPFTIPHST TRDTSLKGFY IPKGRCVFVN QWQINHDQKL WVNPSEFLPE RFLTPDGAID KVLSEKVIIF GMGKRKCIGE TIARWEVFLF LAILLQRVEF SVPLGVKVDM TPIYGLTMKH ACCEHFQMQL RS

Kreuzreaktivität: Human

Produktmerkmale: Antibody reactive against mammalian transfected lysate.

Immunogen: CYP1A1 (NP_000490.1, 1 a.a. ~ 512 a.a) full-length human protein.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-CYP1A1 Antikörper (ABIN947763)

Zapletal, Tylichová, Neča, Kohoutek, Machala, Milcová, Pokorná, Topinka, Moyer, Hofmanová, Kozubík, Vondráček: "Butyrate alters expression of cytochrome P450 1A1 and metabolism of benzo[a]pyrene via its histone deacetylase activity in colon epithelial cell models." in: Archives of toxicology, Vol. 91, Issue 5, pp. 2135-2150, (2016) (PubMed).

Kabátková, Zapletal, Tylichová, Ne?a, Machala, Milcová, Topinka, Kozubík, Vondrá?ek: "Inhibition of ?-catenin signalling promotes DNA damage elicited by benzo[a]pyrene in a model of human colon cancer cells via CYP1 deregulation." in: Mutagenesis, Vol. 30, Issue 4, pp. 565-76, (2015) (PubMed).

Details zu CYP1A1

Target: CYP1A1 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1))

Andere Bezeichnung: CYP1A1 (CYP1A1 Produkte)

Synonyme: AHH antikoerper, AHRR antikoerper, CP11 antikoerper, CYP1 antikoerper, P1-450 antikoerper, P450-C antikoerper, P450DX antikoerper, Cyp1a2 antikoerper, P450-1 antikoerper, cyp1a1 antikoerper, CYP1A1 antikoerper, CYPIA1 antikoerper, Cyp45c antikoerper, Cypc45c antikoerper, P-450MC antikoerper, wu:fb63b04 antikoerper, zfCYP1A antikoerper, zgc:109747 antikoerper, ahh antikoerper, ahrr antikoerper, cp11 antikoerper, cyp1 antikoerper, cyp1a antikoerper, p1-450 antikoerper, p450-c antikoerper, p450dx antikoerper, cytochrome P450 family 1 subfamily A member 1 antikoerper, cytochrome P450 1A1 antikoerper, cytochrome P450, family 1, subfamily a, polypeptide 1 antikoerper, cytochrome P450, family 1, subfamily A, polypeptide 1 antikoerper, cytochrome P450 family 1 subfamily D polypeptide 1 antikoerper, cytochrome P4501A1 antikoerper, polycyclic hydrocarbon-inducible cytochrome P450c antikoerper, cytochrome P450, family 1, subfamily A antikoerper, cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1 antikoerper, cytochrome P450 family 1 subfamily A member 1 L homeolog antikoerper, CYP1A1 antikoerper, CpipJ_CPIJ010542 antikoerper, Cyp1a1 antikoerper, cyp1d1 antikoerper, LOC100328613 antikoerper, cyp1a antikoerper, LOC102129994 antikoerper, cyp1a1.L antikoerper

Hintergrund: Full Gene Name: cytochrome P450, family 1, subfamily A, polypeptide 1
Synonyms: AHH,AHRR,CP11,CYP1,P1-450,P450-C,P450DX

Gen-ID: 1543

NCBI Accession: NM_000499

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha