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CYP1A1 Antikörper (Middle Region)

CYP1A1 Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen, Schaf, Hund, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2776792
  • Target Alle CYP1A1 Antikörper anzeigen
    CYP1A1 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1))
    Bindungsspezifität
    • 10
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 53
    • 24
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen, Schaf, Hund, Zebrafisch (Danio rerio)
    Wirt
    • 36
    • 24
    • 1
    Kaninchen
    Klonalität
    • 39
    • 22
    Polyklonal
    Konjugat
    • 39
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CYP1A1 Antikörper ist unkonjugiert
    Applikation
    • 47
    • 27
    • 16
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    FKDLNEKFYS FMQKMVKEHY KTFEKGHIRD ITDSLIEHCQ EKQLDENANV
    Homologie
    Cow: 100%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 77%
    Produktmerkmale
    This is a rabbit polyclonal antibody against CYP1A1. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human CYP1A1
    Top Product
    Discover our top product CYP1A1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 512 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CYP1A1 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1))
    Andere Bezeichnung
    CYP1A1 (CYP1A1 Produkte)
    Synonyme
    AHH antikoerper, AHRR antikoerper, CP11 antikoerper, CYP1 antikoerper, P1-450 antikoerper, P450-C antikoerper, P450DX antikoerper, Cyp1a2 antikoerper, P450-1 antikoerper, cyp1a1 antikoerper, CYP1A1 antikoerper, CYPIA1 antikoerper, Cyp45c antikoerper, Cypc45c antikoerper, P-450MC antikoerper, wu:fb63b04 antikoerper, zfCYP1A antikoerper, zgc:109747 antikoerper, ahh antikoerper, ahrr antikoerper, cp11 antikoerper, cyp1 antikoerper, cyp1a antikoerper, p1-450 antikoerper, p450-c antikoerper, p450dx antikoerper, cytochrome P450 family 1 subfamily A member 1 antikoerper, cytochrome P450 1A1 antikoerper, cytochrome P450, family 1, subfamily a, polypeptide 1 antikoerper, cytochrome P450, family 1, subfamily A, polypeptide 1 antikoerper, cytochrome P450 family 1 subfamily D polypeptide 1 antikoerper, cytochrome P4501A1 antikoerper, polycyclic hydrocarbon-inducible cytochrome P450c antikoerper, cytochrome P450, family 1, subfamily A antikoerper, cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1 antikoerper, cytochrome P450 family 1 subfamily A member 1 L homeolog antikoerper, CYP1A1 antikoerper, CpipJ_CPIJ010542 antikoerper, Cyp1a1 antikoerper, cyp1d1 antikoerper, LOC100328613 antikoerper, cyp1a antikoerper, LOC102129994 antikoerper, cyp1a1.L antikoerper
    Hintergrund
    CYP1A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown, however, it is able to metabolize some PAHs to carcinogenic intermediates. CYP1A1 has been associated with lung cancer risk. This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown, however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX
    Protein Interaction Partner: CMTM5, CYB5A,
    Protein Size: 512
    Molekulargewicht
    58 kDa
    Gen-ID
    1543
    NCBI Accession
    NM_000499, NP_000490
    UniProt
    P04798
    Pathways
    Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
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