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SORL1 Antikörper (AA 2159-2214)
SORL1
Reaktivität: Human
ELISA, WB
Wirt: Maus
Monoclonal
7D7B11
unconjugated
Produktdetails anti-SORL1 Antikörper
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Target
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SORL1
(Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1))
Bindungsspezifität
Alle Epitope für SORL1 Antikörper
AA 2159-2214
Reaktivität
Alle Reaktivitäten für SORL1 Antikörper
Human
Wirt
Alle Wirte für SORL1 Antikörper
Maus
Klonalität
Alle Klonalitäten für SORL1 Antikörper
Monoklonal
Konjugat
Alle Konjugate für SORL1 Antikörper
Dieser SORL1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für SORL1 Antikörper
ELISA, Western Blotting (WB)
Immunogen
SORL1 antibody was raised in Mouse using a purified recombinant fragment of SORL1(aa2159-2214) expressed in E. coli as the immunogen.
Klon
7D7B11
Isotyp
IgG1
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Anwendungsinformationen
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Applikationshinweise
ELISA: 1:10,000, WB: 1:500-1:2000 Optimal conditions should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
Lot specific
Buffer
Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handhabung
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 4 °C for short term storage. Store at -20 °C for long term storage.
Details zu SORL1
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Target
SORL1
(Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1))
Andere Bezeichnung
SORL1 (SORL1 Produkte )
Synonyme
SORL1 antikoerper, C11orf32 antikoerper, LR11 antikoerper, LRP9 antikoerper, SORLA antikoerper, SorLA-1 antikoerper, gp250 antikoerper, SorLA antikoerper, 2900010L19Rik antikoerper, AI596264 antikoerper, AW261561 antikoerper, mSorLA antikoerper, Lr11 antikoerper, RGD619914 antikoerper, sortilin related receptor 1 antikoerper, sortilin-related receptor antikoerper, sortilin-related receptor, L(DLR class) A repeats containing antikoerper, sortilin-related receptor, L(DLR class) A repeats-containing antikoerper, sortilin-related receptor, LDLR class A repeats-containing antikoerper, sorl1 antikoerper, LOC582560 antikoerper, SORL1 antikoerper, Sorl1 antikoerper
Hintergrund
SORL1 is a Type I membrane protein that may be involved in cell-cell interaction. SorLA, a single transmembrane receptor, binds LDL and transports it into cells by endocytosis. SorLA is synthesized as a proreceptor which is processed to the mature form by a furin-like propeptidase. It can also bind to RAP (receptor-associated protein). SorLA is a multifunctional endocytis receptor important in lipoprotein and protease uptake. The N-terminal propeptide, which is removed, can be cleaved by furin or homologous proteases. Endogenous SorLA binds the neuropeptide head activator (HA) and is important for HA signaling and function. Synonyms: Monoclonal SORL1 antibody, Anti-SORL1 antibody, Sortilin related receptor L A repeats containing antibody.
Pathways
Smooth Muscle Cell Migration
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