SPACA1 Antikörper (N-Term)

Produktnummer ABIN928305

Produktdetails anti-SPACA1 Antikörper

Target: SPACA1 (Sperm Acrosome Associated 1 (SPACA1))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPACA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Purified

Immunogen: SPACA1 antibody was raised in rabbit using the N terminal of SPACA1 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

SPACA1 Blocking Peptide, catalog no. 33R-9051, is also available for use as a blocking control in assays to test for specificity of this SPACA1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu SPACA1

Target: SPACA1 (Sperm Acrosome Associated 1 (SPACA1))

Andere Bezeichnung: SPACA1 (SPACA1 Produkte)

Synonyme: SAMP32 antikoerper, 1700124L11Rik antikoerper, 4930540L03Rik antikoerper, sperm acrosome associated 1 antikoerper, SPACA1 antikoerper, Spaca1 antikoerper

Hintergrund: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively. Synonyms: Polyclonal SPACA1 antibody, Anti-SPACA1 antibody, sperm acrosome associated 1 antibody, MGC32952 antibody, SAMP32 antibody.