CHRNB3 Antikörper (Middle Region)

Produktnummer ABIN926966

Produktdetails anti-CHRNB3 Antikörper

Target: CHRNB3 (Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Huhn, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHRNB3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Maus, Ratte (Rattus), Hund, Huhn, Frosch

Aufreinigung: Purified

Immunogen: CHRNB3 antibody was raised in rabbit using the middle region of CHRNB3 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.03 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

CHRNB3 Blocking Peptide, catalog no. 33R-10069, is also available for use as a blocking control in assays to test for specificity of this CHRNB3 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu CHRNB3

Target: CHRNB3 (Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3))

Andere Bezeichnung: CHRNB3 (CHRNB3 Produkte)

Synonyme: 5730417K16Rik antikoerper, Acrb3 antikoerper, NACHR antikoerper, CHRNB3 antikoerper, chrnb3 antikoerper, cholinergic receptor nicotinic beta 3 subunit antikoerper, neuronal acetylcholine receptor subunit beta-3 antikoerper, cholinergic receptor, nicotinic, beta polypeptide 3 antikoerper, cholinergic receptor, nicotinic beta 3 L homeolog antikoerper, cholinergic receptor, nicotinic beta 3 antikoerper, cholinergic receptor, nicotinic, beta 3b (neuronal) antikoerper, cholinergic receptor, nicotinic, beta polypeptide 3a antikoerper, CHRNB3 antikoerper, CpipJ_CPIJ012638 antikoerper, Chrnb3 antikoerper, chrnb3.L antikoerper, chrnb3 antikoerper, chrnb3b antikoerper, chrnb3a antikoerper

Hintergrund: Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels nAChRs are pentameric structures that are made up of combinations of individual subunits. CHRNB3 is one of the subunits of nAChR. Twelve neuronal nAChR subunits have been described, alpha2-alpha10 and beta2-beta4. CHRNB3 decreased the channel mean open time and burst length. There was also an increase in single channel slope conductance. On the other hand, the calcium permeability and the pharmacological properties of beta3-containing receptors differed little from those of without beta3. Dysfunction of nAChR has been linked to a number of human diseases such as schizophrenia, Alzheimer's and Parkinson's diseases. nAChRs also play a significant role in nicotine addiction. Synonyms: Polyclonal CHRNB3 antibody, Anti-CHRNB3 antibody, cholinergic receptor, nicotinic, beta 3 antibody.