CHRNB3 Antikörper (AA 25-232)

Produktnummer ABIN5684151

Produktdetails anti-CHRNB3 Antikörper

Target: CHRNB3 (Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3))

Bindungsspezifität: AA 25-232

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CHRNB3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human CHRNB3 (AA: extra 25-232) expressed in E. coli.

Klon: 4C1H2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu CHRNB3

Target: CHRNB3 (Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3))

Andere Bezeichnung: CHRNB3 (CHRNB3 Produkte)

Synonyme: 5730417K16Rik antikoerper, Acrb3 antikoerper, NACHR antikoerper, CHRNB3 antikoerper, chrnb3 antikoerper, cholinergic receptor nicotinic beta 3 subunit antikoerper, neuronal acetylcholine receptor subunit beta-3 antikoerper, cholinergic receptor, nicotinic, beta polypeptide 3 antikoerper, cholinergic receptor, nicotinic beta 3 L homeolog antikoerper, cholinergic receptor, nicotinic beta 3 antikoerper, cholinergic receptor, nicotinic, beta 3b (neuronal) antikoerper, cholinergic receptor, nicotinic, beta polypeptide 3a antikoerper, CHRNB3 antikoerper, CpipJ_CPIJ012638 antikoerper, Chrnb3 antikoerper, chrnb3.L antikoerper, chrnb3 antikoerper, chrnb3b antikoerper, chrnb3a antikoerper

Hintergrund: The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are (hetero)pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of nAChRs are encoded by separate genes and have different primary structure. There are several subtypes of neuronal nAChRs that vary based on which homologous subunits are arranged around the central channel. They are classified as alpha-subunits if, like muscle alpha-1 (MIM 100690), they have a pair of adjacent cysteines as part of the presumed acetylcholine binding site. Subunits lacking these cysteine residues are classified as beta-subunits (Groot Kormelink and Luyten, 1997 [PubMed 9009220]). Elliott et al. (1996) [PubMed 8906617] stated that the proposed structure for each subunit is a conserved N-terminal extracellular domain followed by 3 conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region.

Molekulargewicht: 52.7 kDa

Gen-ID: 1142

HGNC: 5169