PAI1 Antikörper

Produktnummer ABIN926100

Produktdetails anti-PAI1 Antikörper

Target: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Reaktivität: Human

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser PAI1 Antikörper ist unkonjugiert

Applikation: Bitte anfragen

Aufreinigung: Affinity chromatography purified

Immunogen: PAI1 antibody was raised in sheep using Recombinant Plasminogen Activator Inhibitor-1 prepared from bacterial extracts as the immunogen.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined byt he investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Supplied in liquid form with 10 mM HEPES, pH 7.4, 150 mM NaCl, 50 % (v/v) glycerol.

Handhabung: Avoid repeated freeze/thaw cycles.
Product will become viscous but will not freeze. Avoid storage in frost-free freezers. Allow product to warm to room temperature and gently mix before use.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -10 to -20 °C.

Details zu PAI1

Target: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Andere Bezeichnung: PAI1 (SERPINE1 Produkte)

Synonyme: PAI antikoerper, PAI-1 antikoerper, PAI1 antikoerper, PLANH1 antikoerper, SERPINE1 antikoerper, si:ch211-138a11.1 antikoerper, Planh1 antikoerper, PAI1A antikoerper, Pai1 antikoerper, Pai1aa antikoerper, Planh antikoerper, RATPAI1A antikoerper, serpin family E member 1 antikoerper, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 L homeolog antikoerper, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 antikoerper, serine (or cysteine) peptidase inhibitor, clade E, member 1 antikoerper, SERPINE1 antikoerper, serpine1.L antikoerper, serpine1 antikoerper, Serpine1 antikoerper

Hintergrund: PAI1 is a member of the serpin family of serine protease inhibitors, and is the primary inhibitor of urokinase and tissue plasminogen activator (tPA). PAI-1 is expressed predominantly in adipose, liver and vascular tissues, and is also produced by certain tumor cells. Elevated levels of PAI-1 are associated with obesity, diabetes and cardiovascular disease, and increased production of PAI-1 is induced by various obesity related factors such as TNFa, glucose, insulin, and very-low-density lipoprotein. The obesity related elevation of PAI-1 levels along with the consequential deficiency in plasminogen activators can lead directly to increased risk of thrombosis and other coronary diseases. Synonyms: Polyclonal PAI1 antibody, Anti-PAI1 antibody, PAI-1 antibody, Plasminogen Activator Inhibitor-1 antibody, Serpin E1 antibody.

Pathways: p53 Signalweg, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagie, Smooth Muscle Cell Migration