STAT6 Antikörper

Produktnummer ABIN920869

Produktdetails anti-STAT6 Antikörper

Target: STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STAT6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: Recognizes STAT6.

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Peptide mapped to the carboxy-terminus of human STAT6.

Anwendungsinformationen

Applikationshinweise: Western blot: Use at 10 myL per 5 mL antibody dilution buffer for each mini-gel.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 200 µL containing rabbit IgG in PBS, pH 7.2, with 0.09% sodium azide and 50% glycerol and protein stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu STAT6

Target: STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))

Andere Bezeichnung: STAT6 (STAT6 Produkte)

Synonyme: D12S1644 antikoerper, IL-4-STAT antikoerper, STAT6B antikoerper, STAT6C antikoerper, signal transducer and activator of transcription 6 antikoerper, signal transducer and activator of transcription 6-like antikoerper, STAT6 antikoerper, Stat6 antikoerper, LOC100859543 antikoerper

Hintergrund: STAT6 is a 94 kD member of the STAT (signal transducer and activator of transcription) protein family that is phosphorylated in response to cytokine receptor-associated kinase activity. Phosphorylation of STAT6 induces nuclear translocation to activate transcription. STAT6 is expressed in olfactory cells, bronchial epithelium, adrenal gland, B cells, mast cells, Wilm's tumors and some solid tumors. STAT6 forms homo- and heterotrimers and has been shown to be important in IL-4 mediated biological responses, the induction of Bcl-2 and Bcl-XL, and may also be involved in TH2 differentiation and immunoglobulin class switching. STAT6 is phosphorylated in response to IL-4, IL-13, IL-3 and has been shown to interact with nuclear co-activator 1 (NCOA1), the CREB binding SRC-1 protein, and p300/CBP. Synonyms: Anti-signal transducer and activator of transcription 2, anti-interferon alpha induced transcriptional activator.

Molekulargewicht: 94 kDa

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response