STXBP1 Antikörper (AA 11-110) (Alexa Fluor 350)

Produktnummer ABIN916800

Produktdetails anti-STXBP1 Antikörper (Alexa Fluor 350)

Target: STXBP1 (Syntaxin Binding Protein 1 (STXBP1))

Bindungsspezifität: AA 11-110

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STXBP1 Antikörper ist konjugiert mit Alexa Fluor 350

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Munc18

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu STXBP1

Target: STXBP1 (Syntaxin Binding Protein 1 (STXBP1))

Andere Bezeichnung: STXBP1/Munc18 (STXBP1 Produkte)

Synonyme: MUNC18-1 antikoerper, NSEC1 antikoerper, P67 antikoerper, RBSEC1 antikoerper, UNC18 antikoerper, AI317162 antikoerper, AI326233 antikoerper, MMS10-G antikoerper, Ms10g antikoerper, Munc-18a antikoerper, Munc18-1 antikoerper, N-sec1 antikoerper, Rb-sec1 antikoerper, Sxtbp1 antikoerper, Unc18-1 antikoerper, Unc18h antikoerper, nsec1 antikoerper, fj43h10 antikoerper, stxbp1 antikoerper, wu:fj36d12 antikoerper, wu:fj43h10 antikoerper, zgc:114171 antikoerper, rop antikoerper, unc18 antikoerper, hunc18 antikoerper, rbsec1 antikoerper, munc18-1 antikoerper, MGC146482 antikoerper, ANC18HA antikoerper, NSEC1A antikoerper, Sec1 antikoerper, n-sec1 antikoerper, nSec1 antikoerper, rbSec1 antikoerper, rbSec1A antikoerper, rbSec1B antikoerper, UNC18A antikoerper, si:rp71-10d23.3 antikoerper, syntaxin binding protein 1 antikoerper, syntaxin binding protein 1a antikoerper, syntaxin binding protein 1 L homeolog antikoerper, syntaxin binding protein 1b antikoerper, STXBP1 antikoerper, Stxbp1 antikoerper, stxbp1a antikoerper, stxbp1 antikoerper, Tb09.160.0780 antikoerper, stxbp1.L antikoerper, stxbp1b antikoerper

Hintergrund:

Synonyms: Munc 18 1, Munc 18a, NSec1, p67, Rb sec1, STXBP1, Syntaxin binding protein 1, Unc 18 homolog, Unc 18A, Unc18 1, STXB1_HUMAN, Syntaxin-binding protein 1, MUNC18-1, N-Sec1, Protein unc-18 homolog 1, Unc18-1, Protein unc-18 homolog A, Unc-18A, p67.

Background: Munc18 may participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP binding proteins. It is essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Munc18 can interact with syntaxins 1, 2, and 3 but not syntaxin 4. It may play a role in determining the specificity of intracellular fusion reactions.Mutations in Munc18 can result in accumulations of acetylcholine and paralytic phenotype suggestive of a neurotransmitter release defect. Two Munc18 isoforms have recently been identified. Munc18-1 has been shown to be primarily expressed in brain, while Munc18-2 is expressed in most tissues.

Gen-ID: 6812

UniProt: P61764

Pathways: Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport