Oct-2 Antikörper (AA 11-100) (Alexa Fluor 350)

Produktnummer ABIN909416

Produktdetails anti-Oct-2 Antikörper (Alexa Fluor 350)

Target: Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))

Bindungsspezifität: AA 11-100

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Oct-2 Antikörper ist konjugiert mit Alexa Fluor 350

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Kreuzreaktivität: Human, Maus

Homologie: Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse OCT2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Oct-2

Target: Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))

Andere Bezeichnung: 2-Oct (POU2F2 Produkte)

Synonyme: OCT2 antikoerper, OTF2 antikoerper, Oct-2 antikoerper, Pou2f2 antikoerper, Oct2a antikoerper, Oct2b antikoerper, Otf-2 antikoerper, Otf2 antikoerper, 2-Oct antikoerper, Oct2 antikoerper, POU class 2 homeobox 2 antikoerper, POU domain, class 2, transcription factor 2 antikoerper, solute carrier family 22 (organic cation transporter), member 2 antikoerper, POU2F2 antikoerper, Pou2f2 antikoerper, SLC22A2 antikoerper

Hintergrund:

Synonyms: Otf2, Oct-2, Oct2a, Oct2b, Otf-2, POU domain, class 2, transcription factor 2, Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, Octamer-binding protein 2, Octamer-binding transcription factor 2, Pou2f2, Oct2

Background: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform OCT2.5 activates the U2 small nuclear RNA (snRNA) promoter. Isoforms OCT2.1, OCT2.2 and OCT2.3 activate octamer-containing promoters. Isoforms OCT2.4 and OCT2.5 repress some promoters and activate others. Isoform OCT2.7 is unable to bind to the octamer motif, but can still activate the beta-casein gene promoter at low levels.

Gen-ID: 18987

UniProt: Q00196