Oct-2 Antikörper (AA 112-297)
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- Target Alle Oct-2 (POU2F2) Antikörper anzeigen
- Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))
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Bindungsspezifität
- AA 112-297
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Oct-2 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Staining Methods (StM)
- Aufreinigung
- Purified by Protein A/G
- Immunogen
- Recombinant fragment of human OCT2 protein (around aa 112-297) (exact sequence is proprietary)
- Klon
- Oct2-2136
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product POU2F2 Primärantikörper
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- Applikationshinweise
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Positive Control: Raji or U-937 cells. Spleen or Tonsil.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-80 °C
- Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Haltbarkeit
- 24 months
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- Target
- Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))
- Andere Bezeichnung
- POU2F2 (POU2F2 Produkte)
- Synonyme
- OCT2 antikoerper, OTF2 antikoerper, Oct-2 antikoerper, Pou2f2 antikoerper, Oct2a antikoerper, Oct2b antikoerper, Otf-2 antikoerper, Otf2 antikoerper, 2-Oct antikoerper, Oct2 antikoerper, POU class 2 homeobox 2 antikoerper, POU domain, class 2, transcription factor 2 antikoerper, solute carrier family 22 (organic cation transporter), member 2 antikoerper, POU2F2 antikoerper, Pou2f2 antikoerper, SLC22A2 antikoerper
- Hintergrund
- Oct-2 is a transcription factor of the POU homeo-domain family that binds to the Ig gene octamer sites, regulating B-cell-specific genes. Oct-2 expression can be used as a marker of B-cell lineage and differentiation. Germinal center B-cells, mantle B-cells, monocytoid B-cells, and plasma cells show high level expression of Oct-2. Additionally, mantle cell lymphoma, follicular lymphoma, marginal zone lymphoma, plasmacytoma, Burkitt lymphoma, diffuse large cell lymphoma, diffuse large B-cell lymphoma, Hodgkin lymphoma display increased expression of Oct-2. Several studies of Oct-2 expression have shown a low level expression in pre-B, T-cell, myelomonocytic, and epithelial cell lines, whereas all mature B-cell lines have high levels of expression. In spite of scanty evidence for Oct-2 expression in T cells, it is believed that this factor participates in transcriptional regulation during T-cell activation.
- Molekulargewicht
- 60kDa
- Gen-ID
- 5452
- UniProt
- P09086
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