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Oct-2 Antikörper (AA 112-297)

POU2F2 Reaktivität: Human IHC, StM Wirt: Maus Monoclonal Oct2-2136 unconjugated
Produktnummer ABIN6940358
  • Target Alle Oct-2 (POU2F2) Antikörper anzeigen
    Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))
    Bindungsspezifität
    • 15
    • 12
    • 8
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 112-297
    Reaktivität
    • 74
    • 41
    • 21
    • 18
    • 16
    • 14
    • 3
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 65
    • 8
    • 1
    • 1
    Maus
    Klonalität
    • 64
    • 11
    Monoklonal
    Konjugat
    • 35
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser Oct-2 Antikörper ist unkonjugiert
    Applikation
    • 66
    • 31
    • 24
    • 24
    • 13
    • 9
    • 9
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant fragment of human OCT2 protein (around aa 112-297) (exact sequence is proprietary)
    Klon
    Oct2-2136
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product POU2F2 Primärantikörper
  • Applikationshinweise

    Positive Control: Raji or U-937 cells. Spleen or Tonsil.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))
    Andere Bezeichnung
    POU2F2 (POU2F2 Produkte)
    Synonyme
    OCT2 antikoerper, OTF2 antikoerper, Oct-2 antikoerper, Pou2f2 antikoerper, Oct2a antikoerper, Oct2b antikoerper, Otf-2 antikoerper, Otf2 antikoerper, 2-Oct antikoerper, Oct2 antikoerper, POU class 2 homeobox 2 antikoerper, POU domain, class 2, transcription factor 2 antikoerper, solute carrier family 22 (organic cation transporter), member 2 antikoerper, POU2F2 antikoerper, Pou2f2 antikoerper, SLC22A2 antikoerper
    Hintergrund
    Oct-2 is a transcription factor of the POU homeo-domain family that binds to the Ig gene octamer sites, regulating B-cell-specific genes. Oct-2 expression can be used as a marker of B-cell lineage and differentiation. Germinal center B-cells, mantle B-cells, monocytoid B-cells, and plasma cells show high level expression of Oct-2. Additionally, mantle cell lymphoma, follicular lymphoma, marginal zone lymphoma, plasmacytoma, Burkitt lymphoma, diffuse large cell lymphoma, diffuse large B-cell lymphoma, Hodgkin lymphoma display increased expression of Oct-2. Several studies of Oct-2 expression have shown a low level expression in pre-B, T-cell, myelomonocytic, and epithelial cell lines, whereas all mature B-cell lines have high levels of expression. In spite of scanty evidence for Oct-2 expression in T cells, it is believed that this factor participates in transcriptional regulation during T-cell activation.
    Molekulargewicht
    60kDa
    Gen-ID
    5452
    UniProt
    P09086
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