MDC1 Antikörper (AA 31-130) (Alexa Fluor 488)
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- Target Alle MDC1 Antikörper anzeigen
- MDC1 (Mdc1 (MDC1))
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Bindungsspezifität
- AA 31-130
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MDC1 Antikörper ist konjugiert mit Alexa Fluor 488
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Homologie
- Dog,Cow,Pig,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human MDC1
- Isotyp
- IgG
- Top Product
- Discover our top product MDC1 Primärantikörper
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anti-Mdc1 (MDC1) antibody
MDC1 Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Mdc1 (MDC1) (AA 1-100) antibodyMDC1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Mdc1 (MDC1) (AA 31-130) antibodyMDC1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Mdc1 (MDC1) (N-Term) antibodyMDC1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal P2B11 unconjugated
anti-Mdc1 (MDC1) (N-Term) antibody (HRP)MDC1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal P2B11 HRP
anti-Mdc1 (MDC1) (N-Term) antibody (FITC)MDC1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal P2B11 FITC
anti-Mdc1 (MDC1) (N-Term) antibody (Alkaline Phosphatase (AP))MDC1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal P2B11 Alkaline Phosphatase (AP)
anti-Mdc1 (MDC1) (N-Term) antibody (Biotin)MDC1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal P2B11 Biotin
anti-Mdc1 (MDC1) (N-Term) antibody (PE)MDC1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal P2B11 PE
anti-Mdc1 (MDC1) (N-Term) antibody (APC)MDC1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal P2B11 APC
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- MDC1 (Mdc1 (MDC1))
- Andere Bezeichnung
- Mdc1 (MDC1 Produkte)
- Synonyme
- 6820401C03 antikoerper, AA413496 antikoerper, Nfbd1 antikoerper, mKIAA0170 antikoerper, NFBD1 antikoerper, mediator of DNA damage checkpoint 1 antikoerper, mediator of DNA-damage checkpoint 1 antikoerper, Mdc1 antikoerper, MDC1 antikoerper
- Hintergrund
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Synonyms: NFBD1, Mediator of DNA damage checkpoint protein 1, Nuclear factor with BRCT domains 1, MDC1, KIAA0170
Background: Required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. May serve as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage marked by 'Ser-139' phosphorylation of histone H2AFX. Also required for downstream events subsequent to the recruitment of these proteins. These include phosphorylation and activation of the ATM, CHEK1 and CHEK2 kinases, and stabilization of TP53 and apoptosis. ATM and CHEK2 may also be activated independently by a parallel pathway mediated by TP53BP1.
- Gen-ID
- 9656
- UniProt
- Q14676
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