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MDC1 Antikörper (AA 1-100)

MDC1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6143659
  • Target Alle MDC1 Antikörper anzeigen
    MDC1 (Mdc1 (MDC1))
    Bindungsspezifität
    • 22
    • 16
    • 15
    • 10
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reaktivität
    • 59
    • 54
    • 16
    • 12
    • 11
    • 2
    • 1
    • 1
    Human
    Wirt
    • 49
    • 37
    Kaninchen
    Klonalität
    • 49
    • 37
    Polyklonal
    Konjugat
    • 29
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MDC1 Antikörper ist unkonjugiert
    Applikation
    • 66
    • 30
    • 14
    • 13
    • 13
    • 13
    • 11
    • 10
    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Sequenz
    MEDTQAIDWD VEEEEETEQS SESLRCNVEP VGRLHIFSGA HGPEKDFPLH LGKNVVGRMP DCSVALPFPS ISKQHAEIEI LAWDKAPILR DCGSLNGTQI
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MDC1 (NP_055456.2).
    Isotyp
    IgG
    Top Product
    Discover our top product MDC1 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MDC1 (Mdc1 (MDC1))
    Andere Bezeichnung
    MDC1 (MDC1 Produkte)
    Synonyme
    6820401C03 antikoerper, AA413496 antikoerper, Nfbd1 antikoerper, mKIAA0170 antikoerper, NFBD1 antikoerper, mediator of DNA damage checkpoint 1 antikoerper, mediator of DNA-damage checkpoint 1 antikoerper, Mdc1 antikoerper, MDC1 antikoerper
    Hintergrund
    The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.,MDC1,NFBD1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,MDC1
    Molekulargewicht
    116 kDa/195 kDa/197 kDa/226 kDa
    Gen-ID
    9656
    UniProt
    Q14676
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