NCOR1 Antikörper (AA 2301-2400) (Alexa Fluor 647)

Produktnummer ABIN907775

Produktdetails anti-NCOR1 Antikörper (Alexa Fluor 647)

Target: NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

Bindungsspezifität: AA 2301-2400

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCOR1 Antikörper ist konjugiert mit Alexa Fluor 647

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NC0R1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu NCOR1

Target: NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

Andere Bezeichnung: NCoR1 (NCOR1 Produkte)

Synonyme: ncor antikoerper, zgc:56355 antikoerper, 5730405M06Rik antikoerper, A230020K14Rik antikoerper, N-CoR antikoerper, RIP13 antikoerper, Rxrip13 antikoerper, mKIAA1047 antikoerper, N-CoR1 antikoerper, TRAC1 antikoerper, hN-CoR antikoerper, nuclear receptor corepressor 1 antikoerper, nuclear receptor co-repressor 1 antikoerper, nuclear receptor corepressor 1 pseudogene antikoerper, nuclear receptor corepressor 1 S homeolog antikoerper, ncor1 antikoerper, NCOR1 antikoerper, CpipJ_CPIJ002507 antikoerper, LOC100343278 antikoerper, Ncor1 antikoerper, ncor1.S antikoerper

Hintergrund:

Synonyms: RIP13, Rxrip13, hCIT529I10, hN CoR, hNCoR, KIAA1047, MGC104216, N CoR, N Cor/SMRT corepressor Rip13, N CoR1, NCOR 1, NCoR, NCOR1, Nuclear receptor co repressor 1, Nuclear receptor corepressor 1, Retinoid X receptor interacting protein 13, thyroid hormone and retinoic acid receptor associated corepressor 1, thyroid hormone- and retinoic acid receptor-associated corepressor 1, TRAC 1, TRAC1, Nuclear Receptor Corepressor NCoR, NCOR1_MOUSE.

Background: Nuclear co-repressor 2 (N-CoR2) gene (NCOR2, previously called silencing mediator for retinoid and thyroid hormone receptor SMRT) is recruited to nuclear and non-nuclear receptors in a large repressing complex containing also N-CoR1, mSin3 and HDACs. This large complex represses transcription in absence of ligand. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Tissue specificity: Ubiquitous. It is belongs to the N-CoR nuclear receptor corepressors family.

Gen-ID: 9611

Pathways: Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process