NCOR1 Antikörper (AA 1-200)

Produktnummer ABIN6144420

Produktdetails anti-NCOR1 Antikörper

Target: NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

Bindungsspezifität: AA 1-200

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCOR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: MSSSGYPPNQ GAFSTEQSRY PPHSVQYTFP NTRHQQEFAV PDYRSSHLEV SQASQLLQQQ QQQQLRRRPS LLSEFHPGSD RPQERRTSYE PFHPGPSPVD HDSLESKRPR LEQVSDSHFQ RVSAAVLPLV HPLPEGLRAS ADAKKDPAFG GKHEAPSSPI SGQPCGDDQN ASPSKLSKEE LIQSMDRVDR EIAKVEQQIL

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human NCOR1 (NP_006302.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NCOR1

Target: NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

Andere Bezeichnung: NCOR1 (NCOR1 Produkte)

Synonyme: ncor antikoerper, zgc:56355 antikoerper, 5730405M06Rik antikoerper, A230020K14Rik antikoerper, N-CoR antikoerper, RIP13 antikoerper, Rxrip13 antikoerper, mKIAA1047 antikoerper, N-CoR1 antikoerper, TRAC1 antikoerper, hN-CoR antikoerper, nuclear receptor corepressor 1 antikoerper, nuclear receptor co-repressor 1 antikoerper, nuclear receptor corepressor 1 pseudogene antikoerper, nuclear receptor corepressor 1 S homeolog antikoerper, ncor1 antikoerper, NCOR1 antikoerper, CpipJ_CPIJ002507 antikoerper, LOC100343278 antikoerper, Ncor1 antikoerper, ncor1.S antikoerper

Hintergrund: This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.,NCOR1,N-CoR,N-CoR1,PPP1R109,TRAC1,hN-CoR,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Nuclear hormone receptors,Cancer,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Notch Signaling Pathway,Endocrine & Metabolism,Lipid Metabolism,NCOR1

Molekulargewicht: 103 kDa/258 kDa/270 kDa

Gen-ID: 9611

UniProt: O75376

Pathways: Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process