NCOR1 Antikörper (N-Term)

Produktnummer ABIN927384

Der Kaninchen Polyklonal anti-NCOR1 Antikörper (ABIN927384) detektiert spezifisch NCOR1 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Hund.

Kurzübersicht für NCOR1 Antikörper (N-Term) (ABIN927384)

Target: NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

Reaktivität: Human, Maus, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCOR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-NCOR1 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Maus, Hund

Aufreinigung: Purified

Immunogen: NCOR1 antibody was raised in rabbit using the N terminal of NCOR1 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

NCOR1 Blocking Peptide, (ABIN5614933), is also available for use as a blocking control in assays to test for specificity of this NCOR1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu NCOR1

Target: NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

Andere Bezeichnung: NCOR1

Hintergrund: NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. Synonyms: Polyclonal NCOR1 antibody, Anti-NCOR1 antibody, nuclear receptor co-repressor 1 antibody.

Pathways: Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process