STRADA Antikörper (AA 1-100) (Alexa Fluor 350)
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- Target Alle STRADA Antikörper anzeigen
- STRADA (STE20-Related Kinase Adaptor alpha (STRADA))
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Bindungsspezifität
- AA 1-100
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser STRADA Antikörper ist konjugiert mit Alexa Fluor 350
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Maus
- Homologie
- Human,Rat,Dog,Cow,Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human LYK5
- Isotyp
- IgG
- Top Product
- Discover our top product STRADA Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- STRADA (STE20-Related Kinase Adaptor alpha (STRADA))
- Andere Bezeichnung
- LYK5 (STRADA Produkte)
- Synonyme
- fj99g05 antikoerper, zgc:56109 antikoerper, wu:fj99g05 antikoerper, lyk5 antikoerper, LYK5 antikoerper, NY-BR-96 antikoerper, PMSE antikoerper, STRAD antikoerper, Stlk antikoerper, Lyk5 antikoerper, 2610019A05Rik antikoerper, 6030402H20Rik antikoerper, AI480680 antikoerper, E130112C09Rik antikoerper, STE20-related kinase adaptor alpha antikoerper, ste20-related kinase adaptor alpha antikoerper, STRADA antikoerper, strada antikoerper, Strada antikoerper
- Hintergrund
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Synonyms: Serologically defined breast cancer antigen NY BR 96, STRAD alpha, Protein kinase LYK5, STE20 related adapter protein, STRAD, STRAA_HUMAN.
Background: Members of the STE-20 like kinase family are known to stimulate MAPK pathways by directly activating MAPKKK. LYK5 is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity. It specifically binds LKB1 and plays a key role in regulating the tumor suppressor activities of LKB1. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. LYK5-LKB1 interaction results in phosphorylation of LYK5 and enhanced autophosphorylation of LKB1.
- Gen-ID
- 92335
- Pathways
- AMPK Signaling
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