STRADA Antikörper (C-Term)
Kurzübersicht für STRADA Antikörper (C-Term) (ABIN1981302)
Target
Alle STRADA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 303-346, C-Term
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Homologie
- Pr
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This STRADA antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 303-346 amino acids from the C-terminal region of human STRADA.
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Isotyp
- Ig Fraction
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Applikationshinweise
- WB: 1:1000. IF: 1:25. WB: 1:1000. IHC-P: 1:100. FC: 1:25
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Haltbarkeit
- 6 months
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: "GSK-3? controls autophagy by modulating LKB1-AMPK pathway in prostate cancer cells." in: The Prostate, (2015) (PubMed).
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- STRADA (STE20-Related Kinase Adaptor alpha (STRADA))
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Andere Bezeichnung
- STRADA
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Hintergrund
- Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.
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Molekulargewicht
- 48369
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Gen-ID
- 92335
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UniProt
- Q7RTN6
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Pathways
- AMPK Signaling
Target
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