KCNMB1 Antikörper (AA 10-80) (AbBy Fluor® 647)
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- Target Alle KCNMB1 Antikörper anzeigen
- KCNMB1 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1))
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Bindungsspezifität
- AA 10-80
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Reaktivität
- Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KCNMB1 Antikörper ist konjugiert mit AbBy Fluor® 647
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Applikation
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Ratte
- Homologie
- Human,Mouse,Cow,Sheep,Pig,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human KCNMB1
- Isotyp
- IgG
- Top Product
- Discover our top product KCNMB1 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- KCNMB1 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1))
- Andere Bezeichnung
- KCNMB1 (KCNMB1 Produkte)
- Synonyme
- KCNMB1 antikoerper, BKbeta1 antikoerper, K(VCA)beta antikoerper, SLO-BETA antikoerper, hbeta1 antikoerper, hslo-beta antikoerper, k(VCA)beta-1 antikoerper, slo-beta-1 antikoerper, BKBETA antikoerper, potassium calcium-activated channel subfamily M regulatory beta subunit 1 antikoerper, potassium large conductance calcium-activated channel, subfamily M, beta member 1 antikoerper, KCNMB1 antikoerper, Kcnmb1 antikoerper
- Hintergrund
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Synonyms: Calcium-activated potassium channel subunit beta-1, KCNMB1, BK channel subunit beta-1, Charybdotoxin receptor subunit beta-1, K(VCA)beta-1, Maxi K channel subunit beta-1, Slo-beta-1, Slo-beta
Background: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Increases the apparent Ca2+/voltage sensitivity of the KCNMA1 channel. It also modifies KCNMA1 channel kinetics and alters its pharmacological properties. It slows down the activation and the deactivation kinetics of the channel. Acts as a negative regulator of smooth muscle contraction by enhancing the calcium sensitivity to KCNMA1. Its presence is also a requirement for internal binding of the KCNMA1 channel opener dehydrosoyasaponin I (DHS-1) triterpene glycoside and for external binding of the agonist hormone 17-beta-estradiol (E2). Increases the binding activity of charybdotoxin (CTX) toxin to KCNMA1 peptide blocker by increasing the CTX association rate and decreasing the dissociation rate.
- Gen-ID
- 3779
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