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KCNMB1 Antikörper (AA 40-130)

KCNMB1 Reaktivität: Human ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7146338
  • Target Alle KCNMB1 Antikörper anzeigen
    KCNMB1 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1))
    Bindungsspezifität
    • 15
    • 8
    • 8
    • 7
    • 6
    • 4
    • 1
    • 1
    AA 40-130
    Reaktivität
    • 30
    • 16
    • 10
    Human
    Wirt
    • 45
    Kaninchen
    Klonalität
    • 45
    Polyklonal
    Konjugat
    • 10
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KCNMB1 Antikörper ist unkonjugiert
    Applikation
    • 20
    • 19
    • 13
    • 13
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunofluorescence (IF)
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Calcium-activated potassium channel subunit beta-1 protein (40-130AA)
    Isotyp
    IgG
    Top Product
    Discover our top product KCNMB1 Primärantikörper
  • Applikationshinweise
    Recommended dilution: IF:1:50-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    KCNMB1 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1))
    Andere Bezeichnung
    KCNMB1 (KCNMB1 Produkte)
    Synonyme
    KCNMB1 antikoerper, BKbeta1 antikoerper, K(VCA)beta antikoerper, SLO-BETA antikoerper, hbeta1 antikoerper, hslo-beta antikoerper, k(VCA)beta-1 antikoerper, slo-beta-1 antikoerper, BKBETA antikoerper, potassium calcium-activated channel subfamily M regulatory beta subunit 1 antikoerper, potassium large conductance calcium-activated channel, subfamily M, beta member 1 antikoerper, KCNMB1 antikoerper, Kcnmb1 antikoerper
    Hintergrund

    Background: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Increases the apparent Ca(2+)/voltage sensitivity of the KCNMA1 channel. It also modifies KCNMA1 channel kinetics and alters its pharmacological properties. It slows down the activation and the deactivation kinetics of the channel. Acts as a negative regulator of smooth muscle contraction by enhancing the calcium sensitivity to KCNMA1. Its presence is also a requirement for internal binding of the KCNMA1 channel opener dehydrosoyasaponin I (DHS-1) triterpene glycoside and for external binding of the agonist hormone 17-beta-estradiol (E2). Increases the binding activity of charybdotoxin (CTX) toxin to KCNMA1 peptide blocker by increasing the CTX association rate and decreasing the dissociation rate.

    Aliases: BK channel beta subunit antibody, BK channel subunit beta 1 antibody, BK channel subunit beta-1 antibody, BKbeta antibody, BKbeta1 antibody, Calcium activated potassium channel subfamily M subunit beta 1 antibody, Calcium activated potassium channel subunit beta 1 antibody, Calcium activated potassium channel subunit beta antibody, Calcium-activated potassium channel antibody, Calcium-activated potassium channel subunit beta antibody, Calcium-activated potassium channel subunit beta-1 antibody, Charybdotoxin receptor subunit beta 1 antibody, Charybdotoxin receptor subunit beta-1 antibody, Hbeta1 antibody, hslo beta antibody, K(VCA)beta 1 antibody, K(VCA)beta antibody, K(VCA)beta-1 antibody, KCMB1_HUMAN antibody, KCNMB 1 antibody, Kcnmb1 antibody, Large conductance Ca2+ activated K+ channel beta 1 subunit antibody, Maxi K channel beta subunit antibody, Maxi K channel subunit beta 1 antibody, Maxi K channel subunit beta-1 antibody, Potassium large conductance calcium activated channel subfamily M beta member 1 antibody, Slo beta 1 antibody, SLO beta antibody, Slo-beta antibody, Slo-beta-1 antibody, subfamily M subunit beta-1 antibody

    UniProt
    Q16558
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