HBXIP Antikörper (AA 41-91) (Alexa Fluor 555)

Produktnummer ABIN900216

Produktdetails anti-HBXIP Antikörper (Alexa Fluor 555)

Target: HBXIP (Hepatitis B Virus X-Interacting Protein (HBXIP))

Bindungsspezifität: AA 41-91

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HBXIP Antikörper ist konjugiert mit Alexa Fluor 555

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HBXIP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu HBXIP

Target: HBXIP (Hepatitis B Virus X-Interacting Protein (HBXIP))

Andere Bezeichnung: HBXIP (HBXIP Produkte)

Synonyme: HBXIP antikoerper, xip antikoerper, XIP antikoerper, 1110003H18Rik antikoerper, Hbxip antikoerper, late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 antikoerper, Hepatitis B virus X-interacting protein antikoerper, LAMTOR5 antikoerper, xip antikoerper, Lamtor5 antikoerper

Substanzklasse: Viral Protein

Hintergrund:

Synonyms: HBV X interacting protein, HBX interacting protein, Hepatitis B virus X interacting protein, MGC71071, XIP, HBXIP_HUMAN.

Background: HBXIP (Hepatitis B virus X interacting protein) complexes with the C-terminus of hepatitis B virus X protein (HBx) and down-regulates hepatitis B virus (HBV) replication. When complexed to BIRC5, it interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway.

Gen-ID: 10542

Pathways: PI3K-Akt Signalweg, Regulation of Cell Size