FBP1 Antikörper (AA 31-130) (Alexa Fluor 488)

Produktnummer ABIN896896

Produktdetails anti-FBP1 Antikörper (Alexa Fluor 488)

Target: FBP1 (Fructose-1,6-Bisphosphatase 1 (FBP1))

Bindungsspezifität: AA 31-130

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBP1 Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FBP1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu FBP1

Target: FBP1 (Fructose-1,6-Bisphosphatase 1 (FBP1))

Andere Bezeichnung: FBP1 (FBP1 Produkte)

Synonyme: FBP antikoerper, Fbp-2 antikoerper, Fbp2 antikoerper, Fbp3 antikoerper, FBP1 antikoerper, fbp2 antikoerper, Fdp antikoerper, CG10611 antikoerper, CG31692 antikoerper, Dmel\\CG31692 antikoerper, FbPase antikoerper, fbp1 antikoerper, cb598 antikoerper, fb57b01 antikoerper, zgc:64127 antikoerper, id:ibd1091 antikoerper, wu:fb17g10 antikoerper, wu:fb57b01 antikoerper, fdp antikoerper, xcc-b100_0105 antikoerper, fbp1l antikoerper, fk92h02 antikoerper, wu:fk92h02 antikoerper, zgc:64096 antikoerper, fbp antikoerper, fbp1.S antikoerper, fructose-bisphosphatase 1 antikoerper, fructose bisphosphatase 1 antikoerper, Fructose-1,6-bisphosphatase antikoerper, fructose-1,6-bisphosphatase antikoerper, fructose-1,6-bisphosphatase 1 antikoerper, fructose-bisphosphatase class I antikoerper, fructose-1,6-bisphosphatase 1b antikoerper, fbp antikoerper, fructose-1,6-bisphosphatase 1a antikoerper, fructose-bisphosphatase 1 L homeolog antikoerper, FBP1 antikoerper, Fbp1 antikoerper, fbp1 antikoerper, LOC100136618 antikoerper, RR_RS07410 antikoerper, fbp antikoerper, fbp1b antikoerper, fbp1a antikoerper, fbp1.L antikoerper

Hintergrund:

Synonyms: FBP, Fructose-1,6-bisphosphatase 1, FBPase 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase 1, Liver FBPase, FBP1

Background: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity, increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.

Gen-ID: 2203

UniProt: P09467

Pathways: Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Dicarboxylic Acid Transport