AIMP1 Antikörper (AA 201-300) (Alexa Fluor 350)
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- Target Alle AIMP1 Antikörper anzeigen
- AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))
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Bindungsspezifität
- AA 201-300
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser AIMP1 Antikörper ist konjugiert mit Alexa Fluor 350
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human
- Homologie
- Mouse,Rat,Dog,Cow,Pig,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human EMAP2
- Isotyp
- IgG
- Top Product
- Discover our top product AIMP1 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))
- Andere Bezeichnung
- EMAP2 (AIMP1 Produkte)
- Synonyme
- EMAP2 antikoerper, EMAPII antikoerper, HLD3 antikoerper, SCYE1 antikoerper, p43 antikoerper, wu:fa95a05 antikoerper, zgc:154081 antikoerper, AIMP1 antikoerper, 9830137A06Rik antikoerper, AIMP1/p43 antikoerper, Emap2 antikoerper, Scye1 antikoerper, scye1 antikoerper, aminoacyl tRNA synthetase complex interacting multifunctional protein 1 antikoerper, aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 antikoerper, aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 S homeolog antikoerper, AIMP1 antikoerper, aimp1 antikoerper, Aimp1 antikoerper, aimp1.S antikoerper
- Hintergrund
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Synonyms: AIMP 1, Aimp1, AIMP1/p43, AIMP1_HUMAN , Aminoacyl tRNA synthetase complex-interacting multunctional protein 1, ARS interacting multunctional protein 1, ARS-interacting multunctional protein 1, EMAP 2, EMAP-2, EMAP-II, EMAP II, EMAP2, EMAPII, Endothelial monocyte activating polypeptide 2, Endothelial Monocyte Activating Polypeptide, Endothelial monocyte-activating polypeptide 2, Endothelial monocyte-activating polypeptide II, Multisynthase complex auxiliary component p43, Multisynthetase complex auxiliary component p43, p43 antibody Scye 1, Scye1, Small Inducible Cytokine Subfamily E Member 1, Small inducible cytokine subfamily E, member 1 endothelial monocyte-activating.
Background: Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7.
- Gen-ID
- 9255
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