PTK6 Antikörper (AA 201-300) (Alexa Fluor 488)

Produktnummer ABIN885512

Produktdetails anti-PTK6 Antikörper (Alexa Fluor 488)

Target: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Bindungsspezifität: AA 201-300

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTK6 Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus

Homologie: Rat,Cow,Sheep

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Brk/PTK6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PTK6

Target: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Andere Bezeichnung: PTK6 (PTK6 Produkte)

Synonyme: BRK antikoerper, Sik antikoerper, Tksk antikoerper, tks antikoerper, zgc:153964 antikoerper, protein tyrosine kinase 6 antikoerper, PTK6 protein tyrosine kinase 6 antikoerper, PTK6 protein tyrosine kinase 6b antikoerper, PTK6 antikoerper, Ptk6 antikoerper, ptk6b antikoerper

Hintergrund:

Synonyms: Breast tumor kinase, Breast tumour kinase, Protein tyrosine kinase 6, PTK6, Tyrosine protein kinase BRK, PTK6_HUMAN.

Background: This protein encoded is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. Its presence in the nucleus appears to be linked to suppression of tumor progression. The encoded protein has been shown to undergo autophosphorylation.

Gen-ID: 5753