ATG4B Antikörper (AA 85-200) (Alexa Fluor 555)

Produktnummer ABIN883002

Produktdetails anti-ATG4B Antikörper (Alexa Fluor 555)

Target: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Bindungsspezifität: AA 85-200

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATG4B Antikörper ist konjugiert mit Alexa Fluor 555

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ATG4B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ATG4B

Target: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Andere Bezeichnung: Atg4b (ATG4B Produkte)

Synonyme: apg4b antikoerper, APG4B antikoerper, AUTL1 antikoerper, 2510009N07Rik antikoerper, AW048066 antikoerper, Apg4b antikoerper, Atg4bl antikoerper, Autl1 antikoerper, Aut2b2 antikoerper, autophagy related 4B cysteine peptidase antikoerper, autophagy-related 4b antikoerper, Peptidase family C54 protein antikoerper, cysteine protease ATG4B antikoerper, ATG4 autophagy related 4 homolog B (S. cerevisiae) antikoerper, autophagy related 4B, cysteine peptidase antikoerper, autophagy related 4B, cysteine peptidase L homeolog antikoerper, ATG4B antikoerper, Atg4b antikoerper, AT3G59950 antikoerper, Tsp_08582 antikoerper, Tsp_11599 antikoerper, atg4b antikoerper, atg4b.L antikoerper

Hintergrund:

Synonyms: APG4B, AUTL1, Cysteine protease ATG4B, AUT-like 1 cysteine endopeptidase, Autophagin-1, Autophagy-related cysteine endopeptidase 1, Autophagy-related protein 4 homolog B, hAPG4B, ATG4B, KIAA0943

Background: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.

Gen-ID: 23192

UniProt: Q9Y4P1

Pathways: Autophagie