Angiotensin 1 (AA 34-43) Antikörper (Alexa Fluor 350)

Produktnummer ABIN882575

Produktdetails

Target: Angiotensin 1

Bindungsspezifität: AA 34-43

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Alexa Fluor 350

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Spezifität: Immunogen used for this antibody is DRVYIHPFHL, corresponding to amino acids 34-43 of human Angiotensinogen.

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Sheep,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide of human Angiotensin I

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Angiotensin 1

Hintergrund:

Synonyms: AGT, Alpha 1 antiproteinase antitrypsin, Ang I, Ang II, Ang III, Angiotensin 1, Angiotensin, Angiotensin I, Angiotensin II, Angiotensin-2, Angiotensin III, Angiotensin-3, Angiotensinogen, Angiotensinogen serpin peptidase inhibitor clade A member 8, ANGT_HUMAN, Angiotensin 1-10, Angiotensin 1-8, ANHU, Des-Asp[1]-angiotensin II, FLJ92595, FLJ97926, OTTHUMP00000035878, Pre angiotensinogen, Serine or cysteine proteinase inhibitor, Serpin A8, Serpin peptidase inhibitor, clade A, member 8, SERPINA8.

Background: Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. Angiotensin-2: acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone. Angiotensin-3: stimulates aldosterone release. Angiotensin 1-7: is a ligand for the G-protein coupled receptor MAS1. Has vasodilator and antidiuretic effects. Has an antithrombotic effect that involves MAS1-mediated release of nitric oxide from platelets.

Gen-ID: 183