Angiotensin 1 (AA 34-43) Antikörper (HRP)

Produktnummer ABIN733277

Der Kaninchen Polyklonal anti-Angiotensin 1 Antikörper wird verwendet zum Nachweis von Angiotensin 1 in Proben von Maus. Er wurde validiert für WB, ELISA, IHC (fro) und IHC (p).

Kurzübersicht für Angiotensin 1 (AA 34-43) Antikörper (HRP) (ABIN733277)

Target: Angiotensin 1

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails

Bindungsspezifität: AA 34-43

Spezifität: Immunogen used for this antibody is DRVYIHPFHL, corresponding to amino acids 34-43 of human Angiotensinogen.

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Sheep,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide of human Angiotensin I

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Angiotensin 1

Hintergrund:

Synonyms: AGT, Alpha 1 antiproteinase antitrypsin, Ang I, Ang II, Ang III, Angiotensin 1, Angiotensin, Angiotensin I, Angiotensin II, Angiotensin-2, Angiotensin III, Angiotensin-3, Angiotensinogen, Angiotensinogen serpin peptidase inhibitor clade A member 8, ANGT_HUMAN, Angiotensin 1-10, Angiotensin 1-8, ANHU, Des-Asp[1]-angiotensin II, FLJ92595, FLJ97926, OTTHUMP00000035878, Pre angiotensinogen, Serine or cysteine proteinase inhibitor, Serpin A8, Serpin peptidase inhibitor, clade A, member 8, SERPINA8.

Background: Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. Angiotensin-2: acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone. Angiotensin-3: stimulates aldosterone release. Angiotensin 1-7: is a ligand for the G-protein coupled receptor MAS1. Has vasodilator and antidiuretic effects. Has an antithrombotic effect that involves MAS1-mediated release of nitric oxide from platelets.

Gen-ID: 183