IFNAR1 Antikörper (pSer535, pSer538) (Alexa Fluor 488)

Produktnummer ABIN876479

Produktdetails anti-IFNAR1 Antikörper (Alexa Fluor 488)

Target: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Bindungsspezifität: pSer535, pSer538

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IFNAR1 Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Cow,Sheep,Pig,Horse,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human IFNAR1 around the phosphorylation site of Ser535+Ser538

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu IFNAR1

Target: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Andere Bezeichnung: IFNAR1 + (IFNAR1 Produkte)

Synonyme: ifnar1 antikoerper, IFNAR1 antikoerper, CD118 antikoerper, Ifar antikoerper, Ifnar antikoerper, Ifrc antikoerper, Infar antikoerper, AVP antikoerper, IFN-alpha-REC antikoerper, IFNAR antikoerper, IFNBR antikoerper, IFRC antikoerper, IFN-R-1 antikoerper, interferon alpha and beta receptor subunit 1 antikoerper, interferon-alpha/beta receptor alpha chain-like antikoerper, interferon (alpha and beta) receptor 1 antikoerper, interferon alpha/beta receptor 1 antikoerper, IFNAR1 antikoerper, ifnar1 antikoerper, Ifnar1 antikoerper, LOC609830 antikoerper

Hintergrund:

Synonyms: AVP, IFRC, IFNAR, IFNBR, IFN-alpha-REC, Interferon alpha/beta receptor 1, IFN-R-1, IFN-alpha/beta receptor 1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, CRF2-1, Type I interferon receptor 1, IFNAR1

Background: Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. Can also transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway.

Gen-ID: 3454

UniProt: P17181

Pathways: JAK-STAT Signalweg, Hepatitis C