CRTC3 Antikörper

Produktnummer ABIN865461

Produktdetails anti-CRTC3 Antikörper

Target: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Reaktivität: Human, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CRTC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human CRTC3 expressed in E. Coli.

Klon: 5G9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1/500 - 1/2000, IHC: 1/200-1/1000, IF: 1/200-1/1000, ELISA: Propose dilution 1/10000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100g/100l

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu CRTC3

Target: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Andere Bezeichnung: CRTC3 (CRTC3 Produkte)

Synonyme: torc3 antikoerper, MGC146372 antikoerper, 2610312F20Rik antikoerper, 6332415K15Rik antikoerper, AI429792 antikoerper, BC011210 antikoerper, TORC3 antikoerper, RGD1309666 antikoerper, TORC-3 antikoerper, CREB regulated transcription coactivator 3 antikoerper, CREB regulated transcription coactivator 3 L homeolog antikoerper, CRTC3 antikoerper, crtc3 antikoerper, Crtc3 antikoerper, crtc3.L antikoerper

Hintergrund: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR) . Tissue specificity: Predominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain, colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small intestine, spleen and stomach. Synonyms: TORC3, FLJ21868, CRTC3

Molekulargewicht: 68kDa

Gen-ID: 64784

Pathways: SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion