CRTC3 Antikörper

Produktnummer ABIN969068

Produktdetails anti-CRTC3 Antikörper

Target: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Reaktivität: Human, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CRTC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human CRTC3 expressed in E. coli.

Klon: 5G9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-CRTC3 Antikörper (ABIN969068)

Nakayama, Miyabe, Okabe, Sakuma, Ijichi, Hasegawa, Nagatsuka, Shimozato, Inagaki: "Clinicopathological significance of the CRTC3-MAML2 fusion transcript in mucoepidermoid carcinoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 22, Issue 12, pp. 1575-81, (2009) (PubMed).

Fehr, Röser, Heidorn, Hallas, Löning, Bullerdiek: "A new type of MAML2 fusion in mucoepidermoid carcinoma." in: Genes, chromosomes & cancer, Vol. 47, Issue 3, pp. 203-6, (2008) (PubMed).

Details zu CRTC3

Target: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Andere Bezeichnung: CRTC3 (CRTC3 Produkte)

Synonyme: torc3 antikoerper, MGC146372 antikoerper, 2610312F20Rik antikoerper, 6332415K15Rik antikoerper, AI429792 antikoerper, BC011210 antikoerper, TORC3 antikoerper, RGD1309666 antikoerper, TORC-3 antikoerper, CREB regulated transcription coactivator 3 antikoerper, CREB regulated transcription coactivator 3 L homeolog antikoerper, CRTC3 antikoerper, crtc3 antikoerper, Crtc3 antikoerper, crtc3.L antikoerper

Hintergrund:

Description: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR) .Tissue specificity: Predominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain, colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small intestine, spleen and stomach.

Aliases: TORC3, FLJ21868, CRTC3

Molekulargewicht: 68 kDa

Gen-ID: 64784

HGNC: 64784

Pathways: SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion