TFB2M Antikörper (Internal Region)

Produktnummer ABIN783976

Produktdetails anti-TFB2M Antikörper

Target: TFB2M (Transcription Factor B2, Mitochondrial (TFB2M))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser TFB2M Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: KHCFGRRSAT VIDH

Spezifität: Recognizes TFB2M.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_071761.1. Genename: TFB2M

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu TFB2M

Target: TFB2M (Transcription Factor B2, Mitochondrial (TFB2M))

Andere Bezeichnung: TFB2M (TFB2M Produkte)

Synonyme: CG3910 antikoerper, Dmel\\CG3910 antikoerper, TFB2 antikoerper, d-TF2BM antikoerper, d-mtTFB2 antikoerper, TFB2M antikoerper, sb:cb857 antikoerper, hkp1 antikoerper, Hkp1 antikoerper, mtTFB2 antikoerper, mitochondrial transcription factor B2 antikoerper, transcription factor B2, mitochondrial antikoerper, mtTFB2 antikoerper, TFB2M antikoerper, tfb2m antikoerper, Tfb2m antikoerper

Hintergrund: The transcription factors B1 (TFB1M, 607033) and B2 (TFB2M) are necessary for basal transcription of mammalian mitochondrial DNA. Human TFB1M and TFB2M are expressed ubiquitously and can each support promoter-specific mtDNA transcription in a pure recombinant in vitro system containing mitochondrial RNA polymerase and mitochondrial transcription factor A. TFB2M has been found to be at least 1 order of magnitude more active in promoting transcription than TFB1M. Both factors are highly homologous to bacterial rRNA dimethyltransferases, which suggests that an RNA-modifying enzyme has been recruited during evolution to function as a mitochondrial transcription factor.Synonyms: Dimethyladenosine transferase 2 mitochondrial, Hepatitis C virus NS5A-transactivated protein 5, Mitochondrial 12S rRNA dimethylase 2, Mitochondrial transcription factor B2, N'-adenosyl(rRNA) dimethyltransferase 2, NS5ATP5, S-adenosylmethionine-6-N', mtTFB2

Gen-ID: 216

NCBI Accession: NP_071761